突变特征和转录组分类分析作为未知原发性癌

北京哪个医院治疗白癜风 http://yyk.39.net/bj/zhuanke/89ac7.html

SCI

30September

MutationalSignatureandTranscriptomicClassificationAnalysesastheDecisiveDiagnosticToolsforaCancerofUnknownPrimary

BaggeRO,DemirA,KarlssonJ,etal.MutationalSignatureandTranscriptomicClassificationAnalysesastheDecisiveDiagnosticToolsforaCancerofUnknownPrimary.JCOPrecisionOncology:1-25.

JonasA.Nilsson,PhD,GoteborgsUniversitetSahlgrenskaAkademin,SahlgrenskaCancerCenter,Medicinaregatan1G,Plan6,Gothenburg,NA,Sweden;e-mail:jonas.a.nilsson

surgery.gu.se.

Purpose目的

Cancerofunknownprimaryisagroupofmetastatictumorsinwhichthestandarddiagnosticworkupfailstoidentifythesiteoforiginofthetumor.Thepotentialimpactofprecisiononcologyonthisgroupofpatientsislarge,becauseactionabledrivermutationsandacorrectdiagnosiscouldprovidetreatmentoptionsotherwisenotavailableforpatientswiththesefatalcancers.Thisstudyinvestigatedif

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